The event was televised around the world, with estimates putting the viewing figures at 23 million.
In addition, it is thought nearly 2,000 guests were in attendance at the ceremony itself.
It appears none of this was enough to prevent the Duke from making a quick quip to Michael Middleton when the bride-to-be arrived at the altar.
Despite the crowd before them in Westminster Abbey, the Duke is believed to have remarked to Michael Middleton: “We’re supposed to have just a small family affair”.
Lip reader Tina Lannin analysed the footage to decipher what could have been said on the day, although it has not been confirmed by the Royal Family.
Despite the humour, quotes from the ceremony suggest some nerves were high.
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But despite the scale of the event, senior royals appeared to agree the ceremony had gone well – even the Queen, who appeared to tell Camilla, Duchess of Cornwall it had gone “very well.”
Analysts note humour never seems to be far from the royal family. There are multiple reports of the Queen in particular making witty remarks.
On one occasion, Canadian Prime Minister Justin Trudeau remarked during a dinner in Malta that he was the 12th Canadian Prime Minister to hold the post during Her Majesty’s reign.
When the Queen – who was also present – made a toast, she remarked: “Thank you, Mr Prime Minister of Canada, for making me feel so old!”
On another occasion, British television presenter and naturalist Sir David Attenborough was helping to produce the annual Christmas speech in 1991, according to the 1992 BBC Documentary ‘Elizabeth R’.
At one point, the Queen asked Sir Attenborough whether her clothes fitted with the background behind her.
Sir Attenborough confirmed they did, prompting the Queen to say: “It would be jolly awful if you said no”.
Apparently, the quip led to laughs around the room, including from Sir Attenborough.